rdf:type |
|
lifeskim:mentions |
umls-concept:C0012544,
umls-concept:C0041455,
umls-concept:C0181904,
umls-concept:C0221102,
umls-concept:C0242485,
umls-concept:C0376315,
umls-concept:C0392938,
umls-concept:C0596972,
umls-concept:C0728873,
umls-concept:C1157968,
umls-concept:C1280500,
umls-concept:C1368019,
umls-concept:C1514468,
umls-concept:C1521743,
umls-concept:C1524119,
umls-concept:C1704646,
umls-concept:C2267018
|
pubmed:issue |
2
|
pubmed:dateCreated |
1998-3-19
|
pubmed:abstractText |
We have previously shown that the woven pagetic bone in patients with Paget's disease is characterized by an impaired degree of beta-isomerization of C-telopeptides of type I collagen molecules, which results in a preferential urinary excretion of nonisomerized type I collagen C-telopeptide breakdown products (CTX). The aim of this study was to measure the urinary excretion of nonisomerized (alpha) and beta-isomerized (beta) CTX in patients with Paget's disease treated with a bisphosphonate.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
354-60
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9485094-Aged,
pubmed-meshheading:9485094-Aged, 80 and over,
pubmed-meshheading:9485094-Biological Markers,
pubmed-meshheading:9485094-Bone and Bones,
pubmed-meshheading:9485094-Collagen,
pubmed-meshheading:9485094-Collagen Type I,
pubmed-meshheading:9485094-Diphosphonates,
pubmed-meshheading:9485094-Female,
pubmed-meshheading:9485094-Humans,
pubmed-meshheading:9485094-Imidazoles,
pubmed-meshheading:9485094-Isomerism,
pubmed-meshheading:9485094-Male,
pubmed-meshheading:9485094-Middle Aged,
pubmed-meshheading:9485094-Osteitis Deformans,
pubmed-meshheading:9485094-Peptides,
pubmed-meshheading:9485094-Urine
|
pubmed:year |
1998
|
pubmed:articleTitle |
Measurement of urinary excretion of nonisomerized and beta-isomerized forms of type I collagen breakdown products to monitor the effects of the bisphosphonate zoledronate in Paget's disease.
|
pubmed:affiliation |
INSERM, Lyon, France.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|