Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1998-4-16
pubmed:databankReference
pubmed:abstractText
The vascular tissues of flowering plants form networks of interconnected cells throughout the plant body. The molecular mechanisms directing the routes of vascular strands and ensuring tissue continuity within the vascular system are not known, but are likely to depend on general cues directing plant cell orientation along the apical-basal axis. Mutations in the Arabidopsis gene MONOPTEROS (MP) interfere with the formation of vascular strands at all stages and also with the initiation of the body axis in the early embryo. Here we report the isolation of the MP gene by positional cloning. The predicted protein product contains functional nuclear localization sequences and a DNA binding domain highly similar to a domain shown to bind to control elements of auxin inducible promoters. During embryogenesis, as well as organ development, MP is initially expressed in broad domains that become gradually confined towards the vascular tissues. These observations suggest that the MP gene has an early function in the establishment of vascular and body patterns in embryonic and post-embryonic development.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-1332794, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-1516751, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-16653177, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-1675158, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-1889090, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-2901107, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-7532026, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-7658471, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-7757116, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8066087, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8197457, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8431946, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8528287, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8674420, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8904808, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-8983181, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-9165747, http://linkedlifedata.com/resource/pubmed/commentcorrection/9482737-9188533
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0261-4189
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1405-11
pubmed:dateRevised
2010-9-10
pubmed:meshHeading
pubmed-meshheading:9482737-Amino Acid Sequence, pubmed-meshheading:9482737-Arabidopsis, pubmed-meshheading:9482737-Arabidopsis Proteins, pubmed-meshheading:9482737-Chromosome Walking, pubmed-meshheading:9482737-Cloning, Molecular, pubmed-meshheading:9482737-DNA, Complementary, pubmed-meshheading:9482737-DNA, Plant, pubmed-meshheading:9482737-DNA-Binding Proteins, pubmed-meshheading:9482737-Gene Expression Regulation, Plant, pubmed-meshheading:9482737-Genes, Plant, pubmed-meshheading:9482737-Molecular Sequence Data, pubmed-meshheading:9482737-Nuclear Localization Signals, pubmed-meshheading:9482737-Onions, pubmed-meshheading:9482737-Polymorphism, Restriction Fragment Length, pubmed-meshheading:9482737-RNA, Messenger, pubmed-meshheading:9482737-RNA, Plant, pubmed-meshheading:9482737-Recombinant Fusion Proteins, pubmed-meshheading:9482737-Seeds, pubmed-meshheading:9482737-Sequence Analysis, DNA, pubmed-meshheading:9482737-Transcription Factors
pubmed:year
1998
pubmed:articleTitle
The Arabidopsis gene MONOPTEROS encodes a transcription factor mediating embryo axis formation and vascular development.
pubmed:affiliation
Institut für Genetik und Mikrobiologie, Lehrstuhl für Genetik, Universität München, Maria-Ward-Street 1a, 80638 München, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't