Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-2-23
pubmed:abstractText
Palliative surgical procedures offer considerable benefit for the patients with unresectable pancreatic cancer: surgical splanchnicectomy performed in conjunction with biliary-enteric by-pass offers good results as regard pain relief without increased morbidity and mortality. We treated 25 patients with unresectable pancreatic cancer by mean of biliary-enteric by-pass plus bilateral splanchnicectomy performed through different surgical approaches. In this series of patients postoperative mortality was nil, mean survival time was 7.2 months (range 3-14 months). Preoperatively, we assessed all patients as affected by visceral pain: Scott-Huskisson 10 mark-scale value in quantitative assessment of pain was equal or above the 7th mark in 87.5% of patients. One month later in the postoperative follow-up, 96% of the patients had a significant reduction in pain intensity from a preoperative median of 7 mark to a postoperative median of 1.5 mark (p = 0.0001). The mean period free of pain recurrence was 4.8 months. However, after 6 months only 46% of survivors were pain-free with such rate decreasing further to a 10% of survivors after 8 months. Nevertheless, the patients had around 70% of their survival span free of pain. We strongly believe that failure in relief of pain is due to a mistake in preoperative evaluation of the type of pain (somatic and not visceral, or both) and to the onset of somatic pain in the course of the disease rather than to surgical technical errors. Recurrence of pain has been considered inevitable in the biological progression of unresected cancer, and would be treated by combination of therapies, such as non steroidal anti-inflammatory drugs, transaortic coeliac plexus block, narcotics and cervical cordotomy.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0009-4773
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-9
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed-meshheading:9480194-Abdominal Pain, pubmed-meshheading:9480194-Aged, pubmed-meshheading:9480194-Anastomosis, Surgical, pubmed-meshheading:9480194-Common Bile Duct, pubmed-meshheading:9480194-Data Interpretation, Statistical, pubmed-meshheading:9480194-Duodenum, pubmed-meshheading:9480194-Evaluation Studies as Topic, pubmed-meshheading:9480194-Female, pubmed-meshheading:9480194-Follow-Up Studies, pubmed-meshheading:9480194-Gallbladder, pubmed-meshheading:9480194-Hepatic Duct, Common, pubmed-meshheading:9480194-Humans, pubmed-meshheading:9480194-Jejunum, pubmed-meshheading:9480194-Male, pubmed-meshheading:9480194-Middle Aged, pubmed-meshheading:9480194-Pain, Intractable, pubmed-meshheading:9480194-Pain Measurement, pubmed-meshheading:9480194-Palliative Care, pubmed-meshheading:9480194-Pancreatic Neoplasms, pubmed-meshheading:9480194-Recurrence, pubmed-meshheading:9480194-Splanchnic Nerves, pubmed-meshheading:9480194-Stomach, pubmed-meshheading:9480194-Time Factors
pubmed:year
1995
pubmed:articleTitle
[Role of surgical splanchnicectomy in the treatment of pancreatic carcinoma].
pubmed:affiliation
Dipartimento di Scienze Chirurgiche Cattedra di Chirurgia Generale, Università degli Studi, Verona.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract