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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1998-2-24
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pubmed:abstractText |
The action of the Bogomolets' antireticular cytotoxic serum (ACS) as a HIV-1 reproduction inhibitor was studied on the model of human lymphoblastoid cell line MT-4/BRU (acute infection). The HIV-1 reproduction inhibition was estimated according to cell protection level for virus cytopathic action and p24 antigen level in the cultural media. The both tests data on ACS usage in dilutions 1:160-1:640 prove that the virus inhibition effect which may be compared with anti-HIV action of the well-known agent, azidothymidine, was observed. At this dilutions range ACS is devoid of the cell toxicity. The conclusion about perspectivity of ACS usage in the AIDS complex therapy was drawn.
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pubmed:language |
ukr
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1028-0987
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9480019-Anti-HIV Agents,
pubmed-meshheading:9480019-Depression, Chemical,
pubmed-meshheading:9480019-Dose-Response Relationship, Drug,
pubmed-meshheading:9480019-HIV-1,
pubmed-meshheading:9480019-Humans,
pubmed-meshheading:9480019-Immune Sera,
pubmed-meshheading:9480019-Time Factors,
pubmed-meshheading:9480019-Tumor Cells, Cultured,
pubmed-meshheading:9480019-Virus Cultivation,
pubmed-meshheading:9480019-Virus Replication
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pubmed:articleTitle |
[The depression of the reproduction of the human immunodeficiency virus by the use of Bogomolets antireticular cytotoxic serum].
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pubmed:publicationType |
Journal Article,
English Abstract
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