Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1976-10-1
|
pubmed:abstractText |
Norepinephrine was continuously infused for 30 minutes at a rate of 0.2 and 0.3 mug/kg/min into 3 normal human subjects, and plasma vasopressin levels, plasma osmolality, hematocrit value, blood pressure, and heart rate were determined simultaneously. In norepinephrine infusion, an elevation of mean blood pressure and a decrease in heart rate was seen, and the degree of these changes was greater with the infusion at a rate of 0.3 mug/kg/min. Plasma vasopressin levels were suppressed by the infusion, and a dose-response relationship was recognized between the infusion at rates of 0.2 mug/kg/min and 0.3 mug/kg/min, while plasma osmolality did not change, and the hematocrit value rose slightly. These results suggest that norepinephrine-induced water diuresis is related to the suppression of the vasopressin release.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0021-972X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
201-4
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:947939-Adult,
pubmed-meshheading:947939-Blood Pressure,
pubmed-meshheading:947939-Dose-Response Relationship, Drug,
pubmed-meshheading:947939-Female,
pubmed-meshheading:947939-Heart Rate,
pubmed-meshheading:947939-Hematocrit,
pubmed-meshheading:947939-Humans,
pubmed-meshheading:947939-Infusions, Parenteral,
pubmed-meshheading:947939-Male,
pubmed-meshheading:947939-Norepinephrine,
pubmed-meshheading:947939-Osmolar Concentration,
pubmed-meshheading:947939-Vasopressins
|
pubmed:year |
1976
|
pubmed:articleTitle |
Effect of norepinephrine infusion on plasma vasopressin levels in normal human subjects.
|
pubmed:publicationType |
Journal Article
|