Linked Life Data

947846

Source:http://linkedlifedata.com/resource/pubmed/id/947846

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-10-1
pubmed:abstractText
In 18 patients with Crohn's disease, 28 patients with ulcerative colitis, 24 patients with enteritis and in 68 healthy adults lipid A antibody titers were determined by the passive hemolysis test. In addition, 0 antibody titers to polyvalent E. coli, Klebisella, Proteus, and Ps. aeruginosa antigens were measured by indirect hemagglutination. The patients with Crohn's disease showed a statistically significant elevation of the lipid A antibody titers compared with each of the three other groups investigated. The 0 antibody titers for the four polyvalent antigens were also higher in the patients with Crohn's disease than in the other groups. The results indicate that Enterobacteriaceae are involved in the pathogenesis of Crohn's disease. Thus long-term treatment with wide spectrum antibiotics seems to be justified. The determination of lipid A antibody titers may be a useful diagnostic tool in differentiating between Crohn's disease and ulcerative colitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-8126
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
110-2
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Is the pathogenesis of Crohn's disease similar to that juvenile recurrent pyelonephritis? A study of lipid A antibody titers in Crohn's disease, ulcerative colitis and acute enteritis.
pubmed:publicationType
Journal Article