Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-10-1
pubmed:abstractText
Low concentrations of cycloheximide, sufficient to block net protein synthesis in growing normal and cancer cells, had no effect on protein turnover, i.e. either the incorporation of labeled amino acids from media lacking other amino acids essential for growth, or the loss to the medium of amino acids from prelabeled cells. At the concentrations that blocked growth, the rate of amino acid incorporation from complete medium was reduced to the "turnover level" i.e. the rate of incorporation seen in amino acid-deficient media. Protein turnover was inhibited only at higher concentrations of the inhibitor. Qualitatively similar results have been obtained with puromycin, anisomycin, emetin and tylocerebrine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0073-5655
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
346-51
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Some paradoxical effects of inhibitors of protein synthesis on protein turnover in cultured human cells.
pubmed:publicationType
Journal Article