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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1998-3-5
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pubmed:abstractText |
Two distinct types of orthodenticle-related proteins (HpOtxE/L) have been implicated as transcription activators of the aboral ectoderm-specific arylsulfatase (Ars) gene. Here, we describe the structure of HpOtx gene and present evidence that mRNAs of HpOtxE/L are transcribed from a single HpOtx gene by altering the transcription start site and by alternative splicing. By transactivation experiments, we have also demonstrated that HpOtxL activates the Ars promoter in the gastrula-stage embryo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0012-1606
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1998 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
193
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-45
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9473319-Animals,
pubmed-meshheading:9473319-Arylsulfatases,
pubmed-meshheading:9473319-Base Sequence,
pubmed-meshheading:9473319-Codon, Initiator,
pubmed-meshheading:9473319-Drosophila Proteins,
pubmed-meshheading:9473319-Enzyme Activation,
pubmed-meshheading:9473319-Gene Expression Regulation,
pubmed-meshheading:9473319-Genes, Homeobox,
pubmed-meshheading:9473319-Homeodomain Proteins,
pubmed-meshheading:9473319-Luciferases,
pubmed-meshheading:9473319-Molecular Sequence Data,
pubmed-meshheading:9473319-Promoter Regions, Genetic,
pubmed-meshheading:9473319-Protein Structure, Tertiary,
pubmed-meshheading:9473319-Recombinant Fusion Proteins,
pubmed-meshheading:9473319-Sea Urchins,
pubmed-meshheading:9473319-Sequence Analysis, DNA,
pubmed-meshheading:9473319-Transcription, Genetic
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pubmed:year |
1998
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pubmed:articleTitle |
Structure and function of a sea urchin orthodenticle-related gene (HpOtx).
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pubmed:affiliation |
Faculty of Science, Hiroshima University, Kagamiyama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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