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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-3-5
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pubmed:abstractText |
Gene therapy is now being applied to the treatment of wide variety of acquired and inherited diseases. One of the rate-limiting steps for successful gene therapy is the efficiency of gene transfer. A number of different viral systems are being developed for use as vectors for ex vivo and in vivo gene transfer, including retroviruses, adenoviruses, herpes-simplex viruses and adeno-associated viruses. These viral vectors have a number of specific advantages and disadvantages that make them suited to particular gene-therapeutic applications. This review will summarize the current status of the development of viral vectors for gene therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
B
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0167-7799
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-40
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pubmed:dateRevised |
2006-4-21
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pubmed:meshHeading |
pubmed-meshheading:9470229-Adenoviridae,
pubmed-meshheading:9470229-Dependovirus,
pubmed-meshheading:9470229-Gene Therapy,
pubmed-meshheading:9470229-Genetic Vectors,
pubmed-meshheading:9470229-Humans,
pubmed-meshheading:9470229-Retroviridae,
pubmed-meshheading:9470229-Simplexvirus,
pubmed-meshheading:9470229-Viruses
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pubmed:year |
1998
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pubmed:articleTitle |
Viral vectors for gene therapy.
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pubmed:affiliation |
Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, PA 15261, USA. probb@pop.pitt.edu
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pubmed:publicationType |
Journal Article,
Review
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