Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-3-5
pubmed:abstractText
Gene therapy is now being applied to the treatment of wide variety of acquired and inherited diseases. One of the rate-limiting steps for successful gene therapy is the efficiency of gene transfer. A number of different viral systems are being developed for use as vectors for ex vivo and in vivo gene transfer, including retroviruses, adenoviruses, herpes-simplex viruses and adeno-associated viruses. These viral vectors have a number of specific advantages and disadvantages that make them suited to particular gene-therapeutic applications. This review will summarize the current status of the development of viral vectors for gene therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
B
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0167-7799
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-40
pubmed:dateRevised
2006-4-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Viral vectors for gene therapy.
pubmed:affiliation
Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, PA 15261, USA. probb@pop.pitt.edu
pubmed:publicationType
Journal Article, Review