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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1998-4-20
|
| pubmed:abstractText |
All 12 of the human CXC chemokine genes were physically mapped using gene-specific PCR primers and the GenBridge 4 radiation hybrid panel. Nine genes, PF4, PF4V1, GRO1, GCP2, PPBP, IL8, GRO2, GRO3, and SCYB5, were assigned within a 1.8-cR interval of one another on 4q. Two additional genes, MIG and INP10, map within 0.5 cR of each another and 6 cR distal to the above-mentioned group. The final gene, SDF1, is localized on 10q. Phylogenetic analyses of amino acid sequences revealed that SDF1 is the most divergent member and that the physically separated MIG-INP10 pair constitutes a distinct evolutionary lineage.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0888-7543
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
47
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
136-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9465307-Chemokines, CXC,
pubmed-meshheading:9465307-Chromosome Mapping,
pubmed-meshheading:9465307-Chromosomes, Human, Pair 4,
pubmed-meshheading:9465307-Evolution, Molecular,
pubmed-meshheading:9465307-Humans,
pubmed-meshheading:9465307-Hybrid Cells,
pubmed-meshheading:9465307-Phylogeny,
pubmed-meshheading:9465307-Polymerase Chain Reaction
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Localization of the human CXC chemokine subfamily on the long arm of chromosome 4 using radiation hybrids.
|
| pubmed:affiliation |
Intramural Research Support Program, SAIC Frederick, National Cancer Institute-Frederick Cancer Research and Development Center, Maryland 21702-1201, USA. modi@ncifcrf.gov
|
| pubmed:publicationType |
Journal Article
|