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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1998-2-26
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pubmed:databankReference |
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pubmed:abstractText |
In a recent serological survey among 143 ex-captive orang-utans two individuals were found that reacted positive in an ELISA detecting antibodies which cross-react with human T-lymphotropic virus type I (HTLV-I) antigens. Infection of both animals with an HTLV-I or simian T-lymphotropic virus (STLV)-like virus was confirmed by Western blot analysis. A third wild-caught animal, which was not part of the original serological survey, was also found to be infected with an HTLV-related virus in a diagnostic PCR assay and Western blot assay. Nucleotide sequence analysis of the 709 bp PCR fragment from the tax/rex region of the HTLV/STLV genome confirmed infection of orang-utans with an STLV similar to but clearly distinct from other Asian STLVs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Deltaretrovirus Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Deltaretrovirus Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, env,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, gag,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, rex,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, tax,
http://linkedlifedata.com/resource/pubmed/chemical/Retroviridae Proteins, Oncogenic,
http://linkedlifedata.com/resource/pubmed/chemical/env Gene Products, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/gag Gene Products, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/gp21 protein, Human T-lymphotropic...,
http://linkedlifedata.com/resource/pubmed/chemical/gp46 protein, Human T-cell...,
http://linkedlifedata.com/resource/pubmed/chemical/p19 protein, Human T-lymphotropic...,
http://linkedlifedata.com/resource/pubmed/chemical/p24 protein, Human T-lymphotropic...
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-1317
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
79 ( Pt 1)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
51-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9460922-Amino Acid Sequence,
pubmed-meshheading:9460922-Animals,
pubmed-meshheading:9460922-Animals, Wild,
pubmed-meshheading:9460922-Base Sequence,
pubmed-meshheading:9460922-Blotting, Western,
pubmed-meshheading:9460922-DNA, Viral,
pubmed-meshheading:9460922-Deltaretrovirus Antibodies,
pubmed-meshheading:9460922-Deltaretrovirus Antigens,
pubmed-meshheading:9460922-Deltaretrovirus Infections,
pubmed-meshheading:9460922-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9460922-Gene Products, env,
pubmed-meshheading:9460922-Gene Products, gag,
pubmed-meshheading:9460922-Gene Products, rex,
pubmed-meshheading:9460922-Gene Products, tax,
pubmed-meshheading:9460922-Humans,
pubmed-meshheading:9460922-Indonesia,
pubmed-meshheading:9460922-Molecular Sequence Data,
pubmed-meshheading:9460922-Monkey Diseases,
pubmed-meshheading:9460922-Phylogeny,
pubmed-meshheading:9460922-Pongo pygmaeus,
pubmed-meshheading:9460922-Retroviridae Proteins, Oncogenic,
pubmed-meshheading:9460922-Sequence Homology, Amino Acid,
pubmed-meshheading:9460922-Simian T-lymphotropic virus 1,
pubmed-meshheading:9460922-env Gene Products, Human Immunodeficiency Virus,
pubmed-meshheading:9460922-gag Gene Products, Human Immunodeficiency Virus
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pubmed:year |
1998
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pubmed:articleTitle |
Characterization of a simian T-lymphotropic virus from a wild-caught orang-utan (Pongo pygmaeus) from Kalimantan, Indonesia.
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pubmed:affiliation |
Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands. verschoor@bprc.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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