Linked Life Data

9460226

Source:http://linkedlifedata.com/resource/pubmed/id/9460226

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1998-3-5
pubmed:abstractText
1. The exposure of cultured bovine bronchial epithelial cells to 2-naphthol and catechol (10-100 microM) induced a squamous phenotype and inhibited cell proliferation. Phenol and cresol did not have these effects at up to 100 microM. 2. These effects occurred below cytotoxic levels and cell proliferation resumed subsequent to removal of the exposures. 3. Induction of the squamous phenotype was antagonized by retinoic acid, a known morphogenic hormone for several airway epithelial cell culture model systems. 4. Purified recombinant bovine phenol sulphotransferase was used to ablate the antiproliferative and squamous inductive effects of catechol on the cultured airway epithelial cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0049-8254
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1201-14
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Induction and prevention of squamous transformation of bronchial epithelial cells by phenolic compounds.
pubmed:affiliation
Department of Biochemistry, Alma College, MI 48801, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.