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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1998-2-19
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pubmed:abstractText |
Primary liver cancer, which most often takes the form of hepatocellular carcinoma (HCC), is among the 10 most common cancers in humans worldwide. In hepatocarcinogenesis, evidence of a multistep process is supported by the marked increase of HCC incidence with age; most HCCs are diagnosed in the second half of life, generally after a long period of chronic liver disease and in frequent association with cirrhosis. This long process may be correlated with the development of multiple genetic lesions, the origin of which currently remain largely unknown. In a previous study, the authors collected data on genomic DNA aberrations in primary HCC by restriction landmark genomic scanning (RLGS), a powerful screening method for the human genome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
454-61
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9452261-Adult,
pubmed-meshheading:9452261-Carcinoma, Hepatocellular,
pubmed-meshheading:9452261-DNA, Neoplasm,
pubmed-meshheading:9452261-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:9452261-Female,
pubmed-meshheading:9452261-Humans,
pubmed-meshheading:9452261-Liver Neoplasms,
pubmed-meshheading:9452261-Male,
pubmed-meshheading:9452261-Middle Aged,
pubmed-meshheading:9452261-Restriction Mapping
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pubmed:year |
1998
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pubmed:articleTitle |
Genomic aberrations in early stage human hepatocellular carcinomas.
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pubmed:affiliation |
Institute for Molecular and Cellular Biology, Osaka University, Japan.
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pubmed:publicationType |
Journal Article
|