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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1980-6-16
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pubmed:abstractText |
Dull pink globules were found within the epidermis in 65% of junctional, 75% of compound, and 25% of intradermal types of Spitz's nevi (the nevi of large spindle and/or epithelioid cells). These globules were PAS-positive, diastase-resistant and also were positive with the trichrome stain. Similar-appearing eosinophilic globules were noted in the epidermis in only 2% of malignant melanomas and in but 0.9% of ordinary melanocytic nevi. The globules in malignant melanomas and in ordinary melanocytic nevi were negative with PAS and trichrome stains. Therefore, the finding of PAS- and trichrome-positive eosinophilic globules within the epidermis is a helpful sign for histologic differentiation of Spitz's nevus from malignant melanoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0193-1091
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-24
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:94511-Diagnosis, Differential,
pubmed-meshheading:94511-Eosine Yellowish-(YS),
pubmed-meshheading:94511-Humans,
pubmed-meshheading:94511-Melanoma,
pubmed-meshheading:94511-Nevus,
pubmed-meshheading:94511-Skin,
pubmed-meshheading:94511-Skin Neoplasms,
pubmed-meshheading:94511-Staining and Labeling
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pubmed:year |
1979
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pubmed:articleTitle |
Eosinophilic globules in Spitz's nevi. New findings and a diagnostic sign.
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pubmed:publicationType |
Journal Article
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