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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1998-3-17
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pubmed:abstractText |
Six strains of equine infectious anemia virus (EIAV) were recovered from febrile and non-febrile stages of a horse experimentally infected with the P337-V70 strain given once to a horse. The env gp90 genes of the isolates, the P337-V70 and P337-V26, avirulent virus derived from the P337-V70 strain, were sequenced. A comparison of the gp90 gene sequences revealed that amino acid variations among the viruses tested showed as high as 8.2 to 11.5%. In addition, the comparison also indicated that the isolates that recovered from the non-febrile stage were contained in nucleotide insertions in the principal neutralizing domain (PND) region. The insertions were arranged regularly with smaller segments. The nucleotide sequence of the P337-V26 gp90 gene was found to contain a six-nucleotides insertion and seven nucleotide substitutions outside the PND region, when compared with that of the P337-V70 strain.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0916-7250
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1089-95
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9450237-Amino Acid Sequence,
pubmed-meshheading:9450237-Animals,
pubmed-meshheading:9450237-Base Sequence,
pubmed-meshheading:9450237-DNA, Viral,
pubmed-meshheading:9450237-Equine Infectious Anemia,
pubmed-meshheading:9450237-Female,
pubmed-meshheading:9450237-Genes, Viral,
pubmed-meshheading:9450237-Genetic Variation,
pubmed-meshheading:9450237-Horses,
pubmed-meshheading:9450237-Infectious Anemia Virus, Equine,
pubmed-meshheading:9450237-Molecular Sequence Data,
pubmed-meshheading:9450237-Polymerase Chain Reaction,
pubmed-meshheading:9450237-Viral Envelope Proteins
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pubmed:year |
1997
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pubmed:articleTitle |
Genetic variation of envelope gp90 gene of equine infectious anemia virus isolated from an experimentally infected horse.
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pubmed:affiliation |
National Institute of Animal Health, Ibaraki, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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