Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11-12
pubmed:dateCreated
1998-2-17
pubmed:abstractText
This paper describes a new technique for prophylactic treatment of recurrent mandibular dislocation using injection of botulinum toxin A (BtA) into the lateral pterygoid muscles. BtA temporarily weakens muscles by blocking acetylcholine release, and thus operates through a principle different from established treatments such as joint sclerosant therapy, eminectomy or Dautry's procedure. The patient suffered recurrent mandibular dislocations caused by tardive dystonia. We injected 75 mu BtA percutaneously into each lateral pterygoid muscle under electromyographic guidance. No further dislocations occurred over the subsequent 10 months, and follow-up continues. There were no immediate or delayed side effects. More experience is required before this becomes an established treatment. BtA is usually given in outpatients, and is less invasive or destructive than previous options. It may not be suitable if dislocation is due to lax ligaments or weak muscles. Operators must be aware that other BtA preparations require a different dose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0007-0610
pubmed:author
pubmed:issnType
Print
pubmed:volume
183
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
415-7
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:9447771-Acetylcholine, pubmed-meshheading:9447771-Aged, pubmed-meshheading:9447771-Ambulatory Care, pubmed-meshheading:9447771-Botulinum Toxins, Type A, pubmed-meshheading:9447771-Chemoprevention, pubmed-meshheading:9447771-Dislocations, pubmed-meshheading:9447771-Dystonia, pubmed-meshheading:9447771-Electromyography, pubmed-meshheading:9447771-Female, pubmed-meshheading:9447771-Follow-Up Studies, pubmed-meshheading:9447771-Humans, pubmed-meshheading:9447771-Injections, Intramuscular, pubmed-meshheading:9447771-Joint Instability, pubmed-meshheading:9447771-Ligaments, Articular, pubmed-meshheading:9447771-Muscle Weakness, pubmed-meshheading:9447771-Neuromuscular Agents, pubmed-meshheading:9447771-Pterygoid Muscles, pubmed-meshheading:9447771-Recurrence, pubmed-meshheading:9447771-Sclerotherapy, pubmed-meshheading:9447771-Temporal Bone, pubmed-meshheading:9447771-Temporomandibular Joint Disorders
pubmed:articleTitle
Medical treatment of recurrent temporomandibular joint dislocation using botulinum toxin A.
pubmed:affiliation
Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool.
pubmed:publicationType
Journal Article, Case Reports