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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1976-8-2
pubmed:abstractText
The total fatty acid composition and the distribution of acyl groups in the positions 1 and 2 of 1,2-diacyl-sn-glycero-3-phosphocholine and 1,2-diacyl-sn-glycero-3-phosphoethanolamine as well as in the molecular species of 1,2-diacyl-sn-glycero-3-phosphocholine from the chick embryo liver have been investigated at various stages of development. The fatty acid content of the main lipid classes from the yolks was also evaluated. The relative percentages of total saturated fatty acids in 1,2-diacyl-sn-glycero-3-phosphocholine remained constant during liver development; however, the levels of both main saturated acids, palmitic and stearic acids, were reciprocally counterbalanced as the age of the embryo proceeded. On the other hand, arachidonic acid decreased with time whereas linoleic acid and docosahexaenoic acid doubled their proportions during development. The relative amounts of total saturated fatty acids from liver 1,2-diacyl-sn-glycero-3-phosphoethanolamine were also constant during all stages of development; however, palmitic/stearic acid ratio did not change with time in this phosphoglyceride. Fatty acid composition of the yolk phosphoglycerides did not change during embryonic development. It should be noted that marked differences between fatty acid composition of choline and ethanolamine phosphoglycerides from the embryo liver and those of the yolk phosphoglycerides were demonstrated. The general patterns of the positional distribution of the acyl groups in choline phosphoglycerides differed from those of ethanolamine phosphoglycerides. Palmitic and stearic acids were only positioned at position 1 in 1,2-diacyl-sn-glycero-3-phosphoethanolamine whereas both fatty acids did not acylate exclusively the position 1 in 1,2-diacyl-sn-glycero-3-phosphocholine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
431
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
62-74
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Age differences in the positional distribution of phosphoglycerides and molecular species of choline phosphoglycerides during development of the chick embryo liver.
pubmed:publicationType
Journal Article