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rdf:type |
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lifeskim:mentions |
umls-concept:C0007272,
umls-concept:C0017262,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0172537,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0256102,
umls-concept:C0475264,
umls-concept:C2911684,
umls-concept:C2936380
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pubmed:issue |
1
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pubmed:dateCreated |
1998-2-17
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pubmed:abstractText |
Remodeling of the injured vascular wall is dependent on the action of several extracellular proteases. Previous studies have shown that expression of matrix metalloproteinases (MMP-2 and MMP-9) is upregulated after vascular injury and that MMP-2 is required for the migration of cultured vascular smooth muscle cells across complex extracellular matrix barriers. The present study examined changes in the expression of membrane-type metalloproteinase (MT-MMP-1), a putative regulator of MMP-2, in the tissue localization of MMP-2, and in the expression of activated and latent forms of MMP-2 and the tissue inhibitor of metalloproteinases, TIMP-2, in rat carotid arteries subjected to balloon catheter injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0009-7322
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pubmed:author |
pubmed-author:BilatoCC,
pubmed-author:BnHH,
pubmed-author:ChengLL,
pubmed-author:CrowM TMT,
pubmed-author:FroehlichJ PJP,
pubmed-author:GluzbandYY,
pubmed-author:JenkinsG MGM,
pubmed-author:LakattaE GEG,
pubmed-author:MASS,
pubmed-author:NaterCC,
pubmed-author:Stetler-StevensonWW
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pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
82-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9443435-Angioplasty, Balloon,
pubmed-meshheading:9443435-Animals,
pubmed-meshheading:9443435-Blotting, Western,
pubmed-meshheading:9443435-Carotid Arteries,
pubmed-meshheading:9443435-Carotid Artery Injuries,
pubmed-meshheading:9443435-Gelatinases,
pubmed-meshheading:9443435-Immunohistochemistry,
pubmed-meshheading:9443435-Male,
pubmed-meshheading:9443435-Matrix Metalloproteinase 2,
pubmed-meshheading:9443435-Matrix Metalloproteinases, Membrane-Associated,
pubmed-meshheading:9443435-Metalloendopeptidases,
pubmed-meshheading:9443435-RNA, Messenger,
pubmed-meshheading:9443435-Rats,
pubmed-meshheading:9443435-Rats, Wistar,
pubmed-meshheading:9443435-Tunica Intima
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pubmed:articleTitle |
Increased expression of membrane-type matrix metalloproteinase and preferential localization of matrix metalloproteinase-2 to the neointima of balloon-injured rat carotid arteries.
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pubmed:affiliation |
Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Md 21224, USA.
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pubmed:publicationType |
Journal Article
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