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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
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pubmed:dateCreated |
1998-1-16
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pubmed:abstractText |
We evaluated the overnight urinary excretion of 6-sulfatoxymelatonin in a group of 347 women (range: 18-69 years). 26 women (range 20-29 years) with normogonadotrophic, hypoestrogenemic amenorrhoea (WHO II) were selected and compared with a group of 26 women menstruating normally (range: 19-30 years) with respect to urinary 6-sulfatoxymelatonin excretion, serum 17 beta-estradiol levels and response to the thyroid releasing hormone (TRH) test. Patients with hyperprolactinemia, hyperandrogenemia, thyroid dysfunction and weight problems were excluded. 6-sulfatoxymelatonin was found to be significantly higher in the amenorrhoeic women than in the controls (p < 0.000001). In the amenorrhoeic patients a statistically significant inverse correlation was found between serum 17 beta-estradiol levels and urinary 6-sulfatoxymelatonin excretion. A positive correlation was obtained between the thyroid stimulation hormone (TSH) value measured at 20 minutes after stimulation and 6-sulfatoxymelatonin excretion. Further clinical research in this field is required to evaluate its clinical impact, especially in patients with secondary amenorrhea.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6-sulfatoxymelatonin,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Melatonin,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin-Releasing Hormone
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0043-5325
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
750-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9441520-Adolescent,
pubmed-meshheading:9441520-Adult,
pubmed-meshheading:9441520-Aged,
pubmed-meshheading:9441520-Amenorrhea,
pubmed-meshheading:9441520-Circadian Rhythm,
pubmed-meshheading:9441520-Estradiol,
pubmed-meshheading:9441520-Female,
pubmed-meshheading:9441520-Humans,
pubmed-meshheading:9441520-Melatonin,
pubmed-meshheading:9441520-Middle Aged,
pubmed-meshheading:9441520-Pineal Gland,
pubmed-meshheading:9441520-Reference Values,
pubmed-meshheading:9441520-Thyrotropin,
pubmed-meshheading:9441520-Thyrotropin-Releasing Hormone
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pubmed:year |
1997
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pubmed:articleTitle |
[6-sulfatoxymelatonin in women with secondary amenorrhea].
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pubmed:affiliation |
Klinische Abteilung für Gynäkologische Endokrinologie und Sterilitätsbehandlung, Universitätsklinik für Frauenheilkunde, AKH Wien, Osterreich.
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pubmed:publicationType |
Journal Article,
English Abstract
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