Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-1-20
pubmed:abstractText
Liver regeneration means the ability of the liver to restore the initial cellular mass after damage of various etiology. The primary mechanism of liver regeneration is not clearly defined yet. According to the recent knowledge the liver regeneration is directed by co-acting of many factors and events, among which the metabolic changes in regenerating liver tissue play important role. The aim of this study is to summarize the most important metabolic changes in the early steps of liver regeneration. The study presents the changes, which are taking place in the liver and in the other tissues and organs during liver regeneration, particularly after partial hepatectomy, but also in other types of liver damage. In the beginning the short overview of genetic changes, which enable the development of metabolic changes, is presented. After that the attention is drawn to the carbohydrate, lipid and protein metabolism. In the part, discussing the lipids, the results of experiments, in which the authors followed the influencing of liver regeneration in the rat after partial hepatectomy by means of parenteral and enteral application of various types of lipids and lipids combined with carnitine, is presented. In the next part the study discusses the metabolism of protein kinases and/or ions and trace elements. The energy metabolism as the necessary part of metabolic events is mentioned after that. In the last part the study draws attention to enzymatic retrodifferentiation in regenerating liver.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0049-5522
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
37-55
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Development of metabolic parameters in the early phases of liver regeneration].
pubmed:affiliation
Klinika gerontologická a metabolická, Fakultní nemocnice, Hradec Králové.
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't