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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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|
pubmed:dateCreated |
1998-3-24
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|
pubmed:abstractText |
The caries inhibitory effect of the hydrogenated derivative of an isomaltooligosaccharides mixture (IMO-H) was examined in vitro and in vivo experiments. IMO-H could not be used as a substrate for the crude glucosyltransferases (GTases) of Streptococcus sobrinus 6715 to synthesize water-insoluble glucan. Moreover, it not only significantly inhibited the synthesis of water-insoluble glucan from sucrose, but also the sucrose-dependent adherence of these growing cells the glass surfaces. In the in vivo experiment, the addition of IMO-H to a sucrose-containing diet resulted in significant reduction of caries development in specific-pathogen-free (SPF) rats infected with S. sobrinus 6715.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
B
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|
pubmed:chemical |
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|
pubmed:status |
MEDLINE
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|
pubmed:month |
Dec
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|
pubmed:issn |
0916-8451
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
2015-8
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9438982-Animals,
pubmed-meshheading:9438982-Bacterial Adhesion,
pubmed-meshheading:9438982-Cariostatic Agents,
pubmed-meshheading:9438982-Dental Caries,
pubmed-meshheading:9438982-Dietary Sucrose,
pubmed-meshheading:9438982-Glucans,
pubmed-meshheading:9438982-Glucosyltransferases,
pubmed-meshheading:9438982-Isomaltose,
pubmed-meshheading:9438982-Oligosaccharides,
pubmed-meshheading:9438982-Rats,
pubmed-meshheading:9438982-Specific Pathogen-Free Organisms,
pubmed-meshheading:9438982-Streptococcus
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|
pubmed:year |
1997
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|
pubmed:articleTitle |
Effects of a hydrogenated isomaltooligosaccharide mixture on glucan synthesis and on caries development in rats.
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|
pubmed:affiliation |
Research and Development Center, Showa Sangyo Co., Ltd., Ibaraki, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
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