Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1980-6-25
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pubmed:abstractText |
The effects of specific antibodies in chronic echovirus type 5 (echo 5) encephalitis were investigated in a patient with x-linked hypogammaglobulinemia. Virus was detected in cerebrospinal fluid (CSF) and blood despite treatment with commercial human gammaglobulin that contained low titers of antibodies to echo 5 (0.6 x 10(4) units per injection). Virus disappeared from blood and CSF when plasma containing high concentrations of antibodies (total dose, 1--4 x 10(4) units/kg) was administered intravenously. Maximal inhibition of virus was achieved in culture and in the patient's CSF when the titer of antibody to echo 5 in CSF was greater than or equal to 16 units/ml. Although the patient died, hyperimmune plasma improved the neurologic status and eliminated detectable virus from the blood and CSF.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
858-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:94337-Agammaglobulinemia,
pubmed-meshheading:94337-Antibodies, Viral,
pubmed-meshheading:94337-Antibody Specificity,
pubmed-meshheading:94337-Blood Transfusion,
pubmed-meshheading:94337-Child, Preschool,
pubmed-meshheading:94337-Chronic Disease,
pubmed-meshheading:94337-Encephalitis,
pubmed-meshheading:94337-Enterovirus B, Human,
pubmed-meshheading:94337-Humans,
pubmed-meshheading:94337-Interferons,
pubmed-meshheading:94337-Male,
pubmed-meshheading:94337-Plasma,
pubmed-meshheading:94337-gamma-Globulins
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pubmed:year |
1979
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pubmed:articleTitle |
Effect of specific antibodies on chronic echovirus type 5 encephalitis in a patient with hypogammaglobulinemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|