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pubmed-article:9428898pubmed:abstractTextFibroblast growth factors (FGFs) play a role in neuronal survival after brain ischemia when administered intrace-rebrally. However, the clinical problems that chronic intracerebral infusion of FGFs involves may restrict its use. The purpose of this study was to analyze if FGFs administered intravenously might afford neuroprotection against transient brain ischemia in the light of new published data that suggest that these polypeptides cross the blood brain-barrier (BBB).lld:pubmed
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pubmed-article:9428898pubmed:authorpubmed-author:Giménez-Galle...lld:pubmed
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pubmed-article:9428898pubmed:pagination77-83; discussion 83-4lld:pubmed
pubmed-article:9428898pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9428898pubmed:year1998lld:pubmed
pubmed-article:9428898pubmed:articleTitleIntravenous fibroblast growth factor penetrates the blood-brain barrier and protects hippocampal neurons against ischemia-reperfusion injury.lld:pubmed
pubmed-article:9428898pubmed:affiliationServicio de Histología, Hospital Universitario Ramón y Cajal, Madrid, Spain.lld:pubmed
pubmed-article:9428898pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9428898pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed