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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1998-1-29
|
| pubmed:abstractText |
Fibroblast growth factors (FGFs) play a role in neuronal survival after brain ischemia when administered intrace-rebrally. However, the clinical problems that chronic intracerebral infusion of FGFs involves may restrict its use. The purpose of this study was to analyze if FGFs administered intravenously might afford neuroprotection against transient brain ischemia in the light of new published data that suggest that these polypeptides cross the blood brain-barrier (BBB).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0090-3019
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
77-83; discussion 83-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9428898-Animals,
pubmed-meshheading:9428898-Autoradiography,
pubmed-meshheading:9428898-Blood-Brain Barrier,
pubmed-meshheading:9428898-Fibroblast Growth Factors,
pubmed-meshheading:9428898-Gerbillinae,
pubmed-meshheading:9428898-Hippocampus,
pubmed-meshheading:9428898-Injections, Intravenous,
pubmed-meshheading:9428898-Neurons,
pubmed-meshheading:9428898-Neuroprotective Agents,
pubmed-meshheading:9428898-Reperfusion Injury
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Intravenous fibroblast growth factor penetrates the blood-brain barrier and protects hippocampal neurons against ischemia-reperfusion injury.
|
| pubmed:affiliation |
Servicio de Histología, Hospital Universitario Ramón y Cajal, Madrid, Spain.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|