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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1998-2-4
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pubmed:abstractText |
Calcitonin gene-related peptide (CGRP) protects the gastric mucosa against injurious stimuli in various experimental models. The underlying mechanism could be the increase in gastric mucosal blood flow (GMBF). A number of endogenous vasodilators exert their effects through the activation of adenosine triphosphate (ATP)-sensitive potassium (KATP) channels on vascular smooth muscle. The present experiments were performed to elucidate whether CGRP increases GMBF through the activation of KATP channels and whether the channels are involved in the protection by CGRP of gastric mucosa.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:AoyagiKK,
pubmed-author:DoiKK,
pubmed-author:FujishimaMM,
pubmed-author:IbayashiSS,
pubmed-author:IidaMM,
pubmed-author:KanamotoKK,
pubmed-author:KawakuboKK,
pubmed-author:NagaoTT,
pubmed-author:SadoshimaSS,
pubmed-author:YamamotoCC,
pubmed-author:YanoYY
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pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9428220-Animals,
pubmed-meshheading:9428220-Benzopyrans,
pubmed-meshheading:9428220-Calcitonin Gene-Related Peptide,
pubmed-meshheading:9428220-Gastric Mucosa,
pubmed-meshheading:9428220-Glyburide,
pubmed-meshheading:9428220-Humans,
pubmed-meshheading:9428220-Ion Channel Gating,
pubmed-meshheading:9428220-Male,
pubmed-meshheading:9428220-Potassium Channel Blockers,
pubmed-meshheading:9428220-Potassium Channels,
pubmed-meshheading:9428220-Rats,
pubmed-meshheading:9428220-Rats, Wistar
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pubmed:year |
1998
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pubmed:articleTitle |
Calcitonin gene-related peptide affords gastric mucosal protection by activating potassium channel in Wistar rat.
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pubmed:affiliation |
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article
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