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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1998-1-22
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pubmed:abstractText |
YNK1 is a 98.3-kDa protein whose sequence was originally deduced from a genomic sequence in Caenorhabditis elegans. It was recently found that YNK1 is homologous to three different proteins implicated in signal transduction, suggesting that YNK1 is a signal transduction protein. In this report we describe the isolation of a full-length cDNA that encodes a splice variant of YNK1, designated YNK1a. We also present evidence that both YNK1 and YNK1a transcripts exist in vivo. Furthermore, using an antibody raised against a YNK1a recombinant protein, we demonstrate that the YNK1 protein is expressed in vivo throughout development.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-3002
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
1354
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-40
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9427532-Animals,
pubmed-meshheading:9427532-Caenorhabditis elegans,
pubmed-meshheading:9427532-Caenorhabditis elegans Proteins,
pubmed-meshheading:9427532-Cloning, Molecular,
pubmed-meshheading:9427532-DNA, Complementary,
pubmed-meshheading:9427532-Gene Expression Regulation, Developmental,
pubmed-meshheading:9427532-Genes, Helminth,
pubmed-meshheading:9427532-Genes, Homeobox,
pubmed-meshheading:9427532-Helminth Proteins,
pubmed-meshheading:9427532-Homeodomain Proteins,
pubmed-meshheading:9427532-RNA, Messenger,
pubmed-meshheading:9427532-RNA Splicing,
pubmed-meshheading:9427532-Sequence Analysis,
pubmed-meshheading:9427532-Sequence Homology, Amino Acid,
pubmed-meshheading:9427532-Signal Transduction,
pubmed-meshheading:9427532-Transcription, Genetic
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pubmed:year |
1997
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pubmed:articleTitle |
Molecular cloning of a splice variant of Caenorhabditis elegans YNK1, a putative element in signal transduction.
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pubmed:affiliation |
Department of Clinical Investigation, The University of Texas, M.D. Anderson Cancer Center, Houston 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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