Linked Life Data

9425591

Source:http://linkedlifedata.com/resource/pubmed/id/9425591

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-2-17
pubmed:abstractText
Immunotherapy has been shown to prevent rhinitis symptoms in seasonal allergic rhinitis, and to prevent anaphylaxis to hymenoptera and fire ant stings. The evidence supporting its effectiveness in the treatment of asthma is much more limited; it appears that clinical trials, until the past year, have only tested therapy for single allergens such as house dust mite, cats, pollen, and mold. In the past year, a double-blind placebo-controlled clinical trial was completed that tested immunotherapy with a mixture of multiple allergen extracts in 121 perennial asthmatic children. This was the first test of treatment with allergen mixtures. The trial showed that over 30% of children underwent a complete or partial remission during the 2.5 years of therapy, but the changes were almost identical in both treatment and placebo control groups. Other trials were reported that examined injection therapy using synthetic fragments of the major allergen responsible for allergic reactions to cats. In this trial, acute rhinitis and asthma during exposure to naturally occurring airborne particles of cat allergen were reduced significantly.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1040-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
582-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Allergen-specific immunotherapy in childhood asthma.
pubmed:affiliation
Department of Pediatrics, Johns Hopkins University School of Medicine, CMSC, Baltimore, MD 21287-3923, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Review, Controlled Clinical Trial