Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-9-25
pubmed:abstractText
1. Re-feeding starved rats increased the biogenesis of sterols in livers, with highest activity at 6h after the start of food intake. 2. Complete deficiency of protein or fat and partial deficiency of carbohydrate in the diet had no effect on sterol biogenesis. 3. Glucose, citrate or pyruvate, when administered intraperitoneally to starved rats, stimulated the biogenesis of sterols only at high concentrations. 4. ATP given intraperitoneally at low concentrations (10mg/rat) stimulated biogenesis of sterols, but not of fatty acids, from [1-14C]acetate. This effect was also obtained with other adenosine compounds, but not with adenine or guanosine. 5. Administration of adenosine compounds to starved rats also increased the incorporation of [1-14C]acetate into sterols in liver slices and also the activity of microsomal 3-hydroxy-3-methylglutaryl-CoA reductase. The results suggest a regulatory role for adenosine compounds in the hepatic biogenesis of isoprenoid compounds.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-1120074, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-1131268, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-12981000, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-13044782, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-13061433, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-13130569, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-13295281, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-13630891, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-14190360, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4243412, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4340705, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4349322, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4364764, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4441486, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-4693507, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5025468, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5025470, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5077855, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5116117, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5348127, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5450235, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5574396, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-5810824, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-6020446, http://linkedlifedata.com/resource/pubmed/commentcorrection/942390-6023607
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0264-6021
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
154
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
639-45
pubmed:dateRevised
2010-9-3
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Stimulation of hepatic biogenesis of sterols on administration of adenosine compounds.
pubmed:publicationType
Journal Article