rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
12
|
pubmed:dateCreated |
1998-1-22
|
pubmed:abstractText |
Late acute rejection affects up to 28% of renal allograft recipients and remains a major risk factor for late graft loss. As donor-origin antigen-presenting cells are depleted with time, T-cell recognition of donor-derived alloantigenic peptides presented by self antigen-presenting cells (the "indirect pathway" of allorecognition) may play a key role in the initiation of late acute rejection episodes.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0041-1337
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
27
|
pubmed:volume |
64
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1823-8
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9422426-Amino Acid Sequence,
pubmed-meshheading:9422426-Animals,
pubmed-meshheading:9422426-Cyclosporine,
pubmed-meshheading:9422426-Cytotoxicity, Immunologic,
pubmed-meshheading:9422426-Drug Administration Schedule,
pubmed-meshheading:9422426-Graft Rejection,
pubmed-meshheading:9422426-Heart Transplantation,
pubmed-meshheading:9422426-Hypersensitivity, Delayed,
pubmed-meshheading:9422426-Immunosuppressive Agents,
pubmed-meshheading:9422426-Isoantibodies,
pubmed-meshheading:9422426-Lymphocyte Activation,
pubmed-meshheading:9422426-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:9422426-Molecular Sequence Data,
pubmed-meshheading:9422426-Peptides,
pubmed-meshheading:9422426-Rats,
pubmed-meshheading:9422426-Rats, Inbred Lew,
pubmed-meshheading:9422426-Rats, Inbred WF,
pubmed-meshheading:9422426-Time Factors
|
pubmed:year |
1997
|
pubmed:articleTitle |
Role of indirect allorecognition in experimental late acute rejection.
|
pubmed:affiliation |
Laboratory of Immunogenetics and Transplantation, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|