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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
345
|
| pubmed:dateCreated |
1998-1-21
|
| pubmed:abstractText |
To examine the hypothesis that different types of dense regular connective tissue may have different repair mechanisms within the synovial space, intrasynovial and extrasynovial autogenous donor flexor tendon grafts were placed within the synovial sheaths of the medial and lateral forepaw digits of dogs. Histologic, ultrastructural, biochemical, and biomechanical analyses were done between 10 days and 6 weeks after tendon grafting. Intrasynovial tendon grafts remained viable when transferred to the synovial space and appeared to heal through an intrinsic process with preservation of the gliding surface and improved functional characteristics. Extrasynovial tendon grafts functioned as a scaffolding for the early ingrowth of new vessels and cells. Early cellular necrosis consistently was followed by the ingrowth of fibrovascular adhesions from the periphery. The formation of dense peripheral adhesions, obliterating the gliding surface of the tendon, led to diminished tendon excursion and proximal interphalangeal joint rotation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0009-921X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
239-47
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:9418646-Animals,
pubmed-meshheading:9418646-Awards and Prizes,
pubmed-meshheading:9418646-Biology,
pubmed-meshheading:9418646-Biomechanics,
pubmed-meshheading:9418646-Blood Vessels,
pubmed-meshheading:9418646-Cell Division,
pubmed-meshheading:9418646-Collagen,
pubmed-meshheading:9418646-Connective Tissue,
pubmed-meshheading:9418646-Dogs,
pubmed-meshheading:9418646-Follow-Up Studies,
pubmed-meshheading:9418646-Forelimb,
pubmed-meshheading:9418646-Graft Survival,
pubmed-meshheading:9418646-Microscopy, Electron,
pubmed-meshheading:9418646-Muscular Diseases,
pubmed-meshheading:9418646-Necrosis,
pubmed-meshheading:9418646-Orthopedics,
pubmed-meshheading:9418646-Research,
pubmed-meshheading:9418646-Rotation,
pubmed-meshheading:9418646-Synovial Membrane,
pubmed-meshheading:9418646-Tendons,
pubmed-meshheading:9418646-Tensile Strength,
pubmed-meshheading:9418646-Tissue Adhesions,
pubmed-meshheading:9418646-Transplantation, Autologous,
pubmed-meshheading:9418646-Wound Healing
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
The Marshall R. Urist Young Investigator Award. Autogenous flexor tendon grafts. Biologic mechanisms for incorporation.
|
| pubmed:affiliation |
Georgia Hand and Microsurgery, Atlanta, USA.
|
| pubmed:publicationType |
Journal Article
|