|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010453,
umls-concept:C0012472,
umls-concept:C0021753,
umls-concept:C0033268,
umls-concept:C0033692,
umls-concept:C0086418,
umls-concept:C0150312,
umls-concept:C0225369,
umls-concept:C0521339,
umls-concept:C1280500,
umls-concept:C1454054,
umls-concept:C1704264
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
1998-1-14
|
|
pubmed:abstractText |
Recombinant human osteogenic protein 1 (OP-1) is an effective stimulator of human cartilage 35S-proteoglycan synthesis. The present study was conducted to determine whether stimulation of human articular chondrocytes with OP-1 can help overcome interleukin-1beta (IL-1beta)-induced suppression of 35S-proteoglycan synthesis.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BMP7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein 7,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/IL1RN protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin 1 Receptor Antagonist...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Proteoglycans,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Sialoglycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
40
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2157-61
|
|
pubmed:dateRevised |
2010-3-24
|
|
pubmed:meshHeading |
pubmed-meshheading:9416852-Adolescent,
pubmed-meshheading:9416852-Adult,
pubmed-meshheading:9416852-Bone Morphogenetic Protein 7,
pubmed-meshheading:9416852-Bone Morphogenetic Proteins,
pubmed-meshheading:9416852-Cartilage, Articular,
pubmed-meshheading:9416852-Cells, Cultured,
pubmed-meshheading:9416852-Child, Preschool,
pubmed-meshheading:9416852-Chondrocytes,
pubmed-meshheading:9416852-Dinoprostone,
pubmed-meshheading:9416852-Down-Regulation,
pubmed-meshheading:9416852-Female,
pubmed-meshheading:9416852-Humans,
pubmed-meshheading:9416852-Infant,
pubmed-meshheading:9416852-Interleukin 1 Receptor Antagonist Protein,
pubmed-meshheading:9416852-Interleukin-1,
pubmed-meshheading:9416852-Male,
pubmed-meshheading:9416852-Proteoglycans,
pubmed-meshheading:9416852-Receptors, Interleukin-1,
pubmed-meshheading:9416852-Recombinant Proteins,
pubmed-meshheading:9416852-Sialoglycoproteins,
pubmed-meshheading:9416852-Transforming Growth Factor beta
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
Effects of recombinant human osteogenic protein 1 on the production of proteoglycan, prostaglandin E2, and interleukin-1 receptor antagonist by human articular chondrocytes cultured in the presence of interleukin-1beta.
|
|
pubmed:affiliation |
Rush Medical College at Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
