Linked Life Data

9416332

Source:http://linkedlifedata.com/resource/pubmed/id/9416332

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1998-2-26
pubmed:abstractText
The temporal pattern of brain edema and apoptosis following cold injury was investigated. Extravasation of Evans blue from the disrupted blood-brain barrier (BBB) maximized immediately after injury and returned to the control level at 24 h. However, water content increased up to 24 h and was maintained at a higher level than the control at 72 h. Apoptotic cells as detected by in situ end labeling were observed in the entire lesion at 24 h. At 72 h after injury, these apoptotic cells were observed in the margin of the lesion, but not in the core. These results suggest that apoptosis contributes to neuronal damage following cold injury and may result from the development of vasogenic edema.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0065-1419
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
234-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Blood-brain barrier disruption, edema formation, and apoptotic neuronal death following cold injury.
pubmed:affiliation
Department of Neurological Surgery, School of Medicine, University of California, San Francisco, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.