Linked Life Data

9410358

Source:http://linkedlifedata.com/resource/pubmed/id/9410358

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
1997-12-4
pubmed:abstractText
After the meta-analysis by Carlsen et al. (1992) showing a decline in human sperm count over the last 50 years, several studies have been made on the sperm characteristics of more or less homogeneous groups of men who were collecting semen in the same center for 10-20 years. A significant decline in sperm count was reported in some studies but not in others. The debate on declining sperm counts is not closed and these studies raised the following important questions: could the differences in results be the reflect of variation in techniques or blas in methodologies? If these phenomena are real, why a deterioration of semen quality in some places and not in others with so important geographical differences of sperm production? What are the possible consequences on human fertility and what are the causes? Unfortunately, there is presently no answer. The danish study provoked extensive discussion on the many possible sources of bias while there was less controversy concerning the studies carried out in a single center despite the extent of limitations of several of them. Recent publications indicated concomitant and increasing alterations of the development and/or function of the male genital tract, various observations in the wildlife and several experimental studies suggesting the possible deleterious role of numerous chemical compounds present in our environment. Therefore, prospective epidemiological studies and fundamental researchs are urgently needed.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1165-1083
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
524-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
[Evolution of male fertility in the last twenty years].
pubmed:affiliation
Service d'Histologie-Embryologie/Biologie de la Reproduction et CECOS, Groupe Hospitalier Cochin-Port-Royal, Paris.
pubmed:publicationType
Journal Article, English Abstract, Review