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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
1998-1-27
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pubmed:abstractText |
Improvements in therapy for patients with B-cell acute lymphoblastic leukemia (ALL) and Burkitt's lymphoma (BL) depend on the identification of subsets of patients who require more intensive therapy. Abnormalities of the p53 gene are the most common molecular lesions in human cancer, and may be of prognostic significance in hematologic malignancies. In this study, we examined the p53 gene status in a group of patients with ALL/BL to determine whether some types of mutants were more frequent in this selected group of patients.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:issn |
0390-6078
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pubmed:author |
pubmed-author:BadeltAA,
pubmed-author:BaigetMM,
pubmed-author:BordesRR,
pubmed-author:BrunetSS,
pubmed-author:CubellsJJ,
pubmed-author:EstivillCC,
pubmed-author:LastTT,
pubmed-author:LettZZ,
pubmed-author:MatesLL,
pubmed-author:NomdedéuJ FJF,
pubmed-author:PardiDD,
pubmed-author:RubiolEE,
pubmed-author:SolerJJ
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pubmed:issnType |
Print
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
550-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9407719-Adolescent,
pubmed-meshheading:9407719-Adult,
pubmed-meshheading:9407719-Aged,
pubmed-meshheading:9407719-Aged, 80 and over,
pubmed-meshheading:9407719-Burkitt Lymphoma,
pubmed-meshheading:9407719-Child,
pubmed-meshheading:9407719-Child, Preschool,
pubmed-meshheading:9407719-DNA Mutational Analysis,
pubmed-meshheading:9407719-Female,
pubmed-meshheading:9407719-Humans,
pubmed-meshheading:9407719-Male,
pubmed-meshheading:9407719-Middle Aged,
pubmed-meshheading:9407719-Tumor Suppressor Protein p53
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pubmed:articleTitle |
Mutational analysis of p53 in 16 cases of acute lymphoblastic leukemia and Burkitt's lymphoma.
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pubmed:affiliation |
Departament d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. jfnomde@santpau.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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