Linked Life Data

9407546

Source:http://linkedlifedata.com/resource/pubmed/id/9407546

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-2-3
pubmed:abstractText
Hepatic neuropeptide Y (NPY) innervation was studied by immunohistochemistry in various mature vertebrates including the eel, carp, bullfrog, turtle, chicken, mouse, rat, guinea pig, dog, monkey, and human. In addition, an ontogenetic study on hepatic NPY was made in developing mice and guinea pigs. In all species examined except the eel, NPY-like immunoreactivity was detected in nerve fibers. In the carp, bullfrog, turtle, chicken, mouse, and rat, NPY-positive fibers were distributed around the wall of hepatic vessels and the bile duct of the Glisson's sheath. The density of NPY-positive fibers increased with evolution. However, in the guinea pig, dog, monkey, and human, numerous NPY-positive fibers were observed not only in the Glisson's sheath but also in the liver parenchyma. Positive fibers formed a dense network that surrounded the hepatocytes. The present immunoelectron microscopic study has confirmed that NPY-positive terminals are closely apposed to hepatocytes. Ontogenically, NPY-positive fibers were first found in the embryonic liver of 19-day-old mice. Positive fibers increased with age, and the highest peak was seen 1 week after birth. However, NPY-positive nerve fibers were present abundantly in Glisson's sheath and in the hepatic parenchyma of neonatal (3 and 7 days old) guinea pigs in a distribution similar to that in mature animals. This ontogenetic pattern suggests that NPY plays a certain role in the developing liver.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1059-910X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Development of neuropeptide Y innervation in the liver.
pubmed:affiliation
Department of Physiology, Shiga University of Medical Science, Otsu, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Review