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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1980-5-23
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pubmed:abstractText |
A micro solid phase radioimmunometric assay has been developed which measures type-specific antibody in human sera to herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). The test is performed by coating wells of microtiter plates with purified HSV-specified glycoproteins, VP123 and VP119, derived from HSV-1- and HSV-2-infected cells, respectively. The coated wells are then incubated with diluted unadsorbed sera and subsequently with radioiodinated goat anti-human IgG reagent. Because these major viral envelope glycoproteins contain type-specific antigenic determinants, type-specific antibodies are preferentially detected in our assay.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-5526
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
115-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:94044-Antibodies, Viral,
pubmed-meshheading:94044-Antibody Specificity,
pubmed-meshheading:94044-Diagnosis, Differential,
pubmed-meshheading:94044-Epitopes,
pubmed-meshheading:94044-Glycoproteins,
pubmed-meshheading:94044-Herpes Simplex,
pubmed-meshheading:94044-Humans,
pubmed-meshheading:94044-Neutralization Tests,
pubmed-meshheading:94044-Radioimmunoassay,
pubmed-meshheading:94044-Simplexvirus,
pubmed-meshheading:94044-Viral Proteins
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pubmed:year |
1979
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pubmed:articleTitle |
Detection of herpesvirus type-specific antibody by a micro solid phase radioimmunometric assay.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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