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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1998-1-30
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pubmed:abstractText |
A 28-year-old woman was referred to us to undergo 131I therapy who had multiple pulmonary metastases from papillary thyroid carcinoma after total thyroidectomy. There was no increased accumulation of a tracer in the pulmonary metastatic foci on whole-body scanning using a 111 MBq diagnostic dose of 131I. However, the pulmonary metastases were gradually decreased in size, and then clearly reduced 8 months after the start of TSH suppression therapy, which was maintained by T3 instead of T4 to bring down the serum TSH level below 0.1 microU/ml. Reduction rates of the foci were 33-76% on chest X-ray. The reduction was confirmed and no new lesions were found on the serial CT scans. Serum thyroglobulin level was lowered 80 to 25 ng/ml by this suppression therapy and progression of disease was not observed under a 54 months' T3 treatment. Thus, TSH suppression therapy might improve survival of patients with differentiated thyroid cancer.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Iodine Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroglobulin,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Triiodothyronine
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-7854
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
925-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9404100-Adult,
pubmed-meshheading:9404100-Carcinoma, Papillary,
pubmed-meshheading:9404100-Female,
pubmed-meshheading:9404100-Humans,
pubmed-meshheading:9404100-Iodine Radioisotopes,
pubmed-meshheading:9404100-Lung Neoplasms,
pubmed-meshheading:9404100-Radiopharmaceuticals,
pubmed-meshheading:9404100-Thyroglobulin,
pubmed-meshheading:9404100-Thyroid Neoplasms,
pubmed-meshheading:9404100-Thyrotropin,
pubmed-meshheading:9404100-Triiodothyronine
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pubmed:year |
1997
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pubmed:articleTitle |
[Successful TSH suppression therapy with triiodothyronine in a patient with pulmonary metastases from differentiated thyroid carcinoma in the absence of 131I uptake].
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pubmed:affiliation |
Department of Surgery, Irumagawa Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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