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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1998-1-2
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pubmed:abstractText |
To clarify the mechanism of brain and spinal cord impairment in Rett syndrome (RS), we measured the cerebrospinal fluid (CSF) levels of substance P in 20 patients with RS including 16 childhood patients and 4 adult patients. Findings were compared with those obtained in age-matched controls and diseased controls. The CSF level of substance P was significantly lower in patients with RS compared with controls. The alteration in the CSF level of substance P may be related to the neurological impairment, especially autonomic dysfunction, and neuropathological involvement of dorsal root ganglia and peripheral nerve observed in RS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0364-5134
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
978-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9403492-Adult,
pubmed-meshheading:9403492-Biological Markers,
pubmed-meshheading:9403492-Case-Control Studies,
pubmed-meshheading:9403492-Child,
pubmed-meshheading:9403492-Child, Preschool,
pubmed-meshheading:9403492-Female,
pubmed-meshheading:9403492-Humans,
pubmed-meshheading:9403492-Male,
pubmed-meshheading:9403492-Predictive Value of Tests,
pubmed-meshheading:9403492-Rett Syndrome,
pubmed-meshheading:9403492-Substance P
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pubmed:year |
1997
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pubmed:articleTitle |
Decreased cerebrospinal fluid levels of substance P in patients with Rett syndrome.
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pubmed:affiliation |
Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume City, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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