Linked Life Data

9402614

Source:http://linkedlifedata.com/resource/pubmed/id/9402614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-2-4
pubmed:abstractText
Oxytocinergic neurons of the paraventricular nucleus (PVN) of the hypothalamus have been implicated in modulating male sexual responses in rats. Previous investigators have shown that cerebrospinal fluid concentrations of oxytocin (OT) increased after ejaculation and that intraventricular administration of OT and electrolytic lesions of the PVN increased temporal measures of male sexual behavior. Recently, we have demonstrated that OT-immunoreactive neurons in the parvocellular subnuclei of the PVN project to lower levels of spinal cord. In the present study, N-methyl-D-aspartic acid lesions, which have been shown to destroy parvocellular PVN neurons while leaving magnocellular neurons intact, were used to evaluate the role of parvocellular neurons on male copulatory behavior and seminal emissions. OT-immunoreactive fibers were reduced in the lower lumbar spinal cord (L5-L6) following N-methyl-D-aspartic acid lesions in the PVN. This reduction was associated with a significant decrease in seminal emission at the time of ejaculation, but mount, intromission and ejaculatory latencies were unaffected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-53
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Effects of paraventricular lesions on sex behavior and seminal emission in male rats.
pubmed:affiliation
Department of Zoology, Michigan State University, East Lansing 48824, USA. ackerma4@pilot.msu.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.