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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1976-9-25
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pubmed:abstractText |
Three patients who developed hypothyroidism after x irradiation to the neck are presented. The first two cases demonstrate that patients can develop clinical and chemical hypothyroidism after a very short interval following radiotherapy. Hypothyroidism developed in the first patient in the absence of surgical manipulation of the neck, or a large iodine load 4 months after receiving 6800 rad of x-ray therapy to his neck for carcinoma of the larynx. The second patient developed hypothyroidism approximately 6 months after his radiotherapy for carcinoma of the esophagus. Both of these patients demonstrated high titers of serum antithyroid antibodies. A third patient with Hodgkin's disease did not manifest clinical symptoms and signs of hypothyroidism until 6 years after radiation therapy. These cases demonstrate the variability of onset of hypothyroidism after radiotherapy and emphasize the need for careful evaluation of thyroid function before and after neck irradiation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-7263
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
180-4
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:940251-Adult,
pubmed-meshheading:940251-Carcinoma, Squamous Cell,
pubmed-meshheading:940251-Esophageal Neoplasms,
pubmed-meshheading:940251-Hodgkin Disease,
pubmed-meshheading:940251-Humans,
pubmed-meshheading:940251-Hypothyroidism,
pubmed-meshheading:940251-Laryngeal Neoplasms,
pubmed-meshheading:940251-Male,
pubmed-meshheading:940251-Middle Aged,
pubmed-meshheading:940251-Neck,
pubmed-meshheading:940251-Radiation Effects,
pubmed-meshheading:940251-Radiotherapy,
pubmed-meshheading:940251-Thyroid Function Tests,
pubmed-meshheading:940251-Vocal Cords,
pubmed-meshheading:940251-X-Ray Therapy
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pubmed:year |
1976
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pubmed:articleTitle |
Hypothyroidism after x irradiation to the neck: three case reports and a brief review of the literature.
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pubmed:publicationType |
Journal Article,
Case Reports
|