Linked Life Data

940225

Source:http://linkedlifedata.com/resource/pubmed/id/940225

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-9-25
pubmed:abstractText
Relationship between pharmacological activities and blood levels of a new anticholinergic agent (SA-504), as well as excretion, and distribution in the gastro-intestinal tract were investigated in cats. The time courses of inhibitory effect of SA-504 on gastric motility were closely related to those of blood levels of SA-504 after intragastric administration of 3H-labelled compound. Effects of SA-504 on the pupil of the eye, heart rate and blood pressure were much less than its inhibitory effects on gastric motility. The contents of 3H-SA-504 in the gastric wall were extremely high as compared with those in the blood and heart. About 23% of the radioactivity administered orally as 3H-SA-504 was excreted into the bile and 20% into the urine during a 24 hour period, suggesting that more than 40% of the dose is absorbed from the alimentary tract of cats within 24 hours.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-15
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Relationship between pharmacological activity and blood level of a new anticholinergic agent, timepidium bromide (SA-504), in cats.
pubmed:publicationType
Journal Article