| pubmed-article:9401354 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0014653 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0026339 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0043250 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0221928 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0443254 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:9401354 | lifeskim:mentions | umls-concept:C1140999 | lld:lifeskim |
| pubmed-article:9401354 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9401354 | pubmed:dateCreated | 1998-1-15 | lld:pubmed |
| pubmed-article:9401354 | pubmed:abstractText | Mechanochemical models based on the Oster-Murray continuum framework have been applied to a variety of biological settings to obtain an understanding of the morphogenesis of living tissues. Wound-healing in mammalian skin is an important example, because a complex sequence of biochemical and biomechanical responses are orchestrated to close a wound by a combination of new tissue formation and wound contraction. Mechanical interactions between dermal fibroblastic cells and the collagen-rich extracellular matrix are crucial in the development of a contracted wound state. We and others have previously proposed mechanochemical models for wound repair to gain a greater understanding of both normal and abnormal healing. In the present work, the existence of spatially varying equilibria of these models is investigated by using a small-stain approximation and phase-plane techniques, with numerical simulations to confirm the analytical predictions. These results are sources of novel insight into the roles of key biological parameters in determining the mechanical properties of a contracted wound. These methods may also be relevant to other morphogenetic scenarios for which similar mechanochemical models have been proposed. | lld:pubmed |
| pubmed-article:9401354 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9401354 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9401354 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9401354 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9401354 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9401354 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:9401354 | pubmed:issn | 0025-5564 | lld:pubmed |
| pubmed-article:9401354 | pubmed:author | pubmed-author:OlsenLL | lld:pubmed |
| pubmed-article:9401354 | pubmed:author | pubmed-author:SherrattJ AJA | lld:pubmed |
| pubmed-article:9401354 | pubmed:author | pubmed-author:MainiP KPK | lld:pubmed |
| pubmed-article:9401354 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9401354 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:9401354 | pubmed:volume | 147 | lld:pubmed |
| pubmed-article:9401354 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9401354 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9401354 | pubmed:pagination | 113-29 | lld:pubmed |
| pubmed-article:9401354 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:meshHeading | pubmed-meshheading:9401354-... | lld:pubmed |
| pubmed-article:9401354 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9401354 | pubmed:articleTitle | Spatially varying equilibria of mechanical models: application to dermal wound contraction. | lld:pubmed |
| pubmed-article:9401354 | pubmed:affiliation | Centre of Mathematical Biology, Mathematical Institute, Oxford, United Kingdom. | lld:pubmed |
| pubmed-article:9401354 | pubmed:publicationType | Journal Article | lld:pubmed |
