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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-7
|
| pubmed:dateCreated |
1998-2-10
|
| pubmed:abstractText |
Amaranthus leucocarpus lectin (ALL) is specific for GalNAc residue found in the inner core of Gal beta 1,3GalNAc alpha 1,O-Ser/Thr disaccharide (T-antigen) or GalNAc alpha 1,O-Ser/Thr (Tn-antigen). Flow cytometric analysis using fluorescein-labeled lectin and monoclonal antibodies against human cell surface markers indicated that 5.7% of mononuclear cells from human healthy donors are recognized by ALL. These cells have the phenotype CD2+CD4+CD19- and most of the lymphocytes recognized are also CD27+, CD45RA+ and CD43+. ALL possesses mitogenic activity on lymphocytes after neuraminidase treatment. Our results indicate that the receptors recognized by ALL could be considered surface markers for naive human T lymphocyte subsets.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0882-0139
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
579-87
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9399101-Flow Cytometry,
pubmed-meshheading:9399101-Humans,
pubmed-meshheading:9399101-Lectins,
pubmed-meshheading:9399101-Leukocytes, Mononuclear,
pubmed-meshheading:9399101-Lymphocyte Activation,
pubmed-meshheading:9399101-Mitogens,
pubmed-meshheading:9399101-Receptors, Cell Surface,
pubmed-meshheading:9399101-T-Lymphocyte Subsets
|
| pubmed:articleTitle |
Amaranthus leucocarpus lectin recognizes human naive T cell subpopulations.
|
| pubmed:affiliation |
Departamento de Bioquímica, Instituto Nacional de Enfermedades Respiratorias, Calzada de Tlalpan, México.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|