Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1998-1-16
|
pubmed:abstractText |
Exciting and demanding biomedical experiments may attract a specific subgroup of people as volunteers. In the present study of selection bias, subjects volunteering in a psychobiological study that included a potentially painful procedure (lumbar puncture) were compared with those who declined to participate, with regard to scores on personality scales administered during a previous investigation of the same subjects. Significant differences were found on the Eysenck Personality Questionnaire and Karolinska Scales of Personality Impulsiveness scale, suggesting an over-representation of impulsive individuals among the volunteers. If the specific subject of investigation has implications for the type of individual who will participate as a healthy volunteer in biomedical research, variation will be introduced, affecting the independent variable, and the conclusions that can be drawn from such research may be questionable.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0001-690X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
96
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
325-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9395148-Adolescent,
pubmed-meshheading:9395148-Adult,
pubmed-meshheading:9395148-Humans,
pubmed-meshheading:9395148-Impulsive Behavior,
pubmed-meshheading:9395148-Male,
pubmed-meshheading:9395148-Personality,
pubmed-meshheading:9395148-Personality Inventory,
pubmed-meshheading:9395148-Psychometrics,
pubmed-meshheading:9395148-Psychophysiology,
pubmed-meshheading:9395148-Research,
pubmed-meshheading:9395148-Selection Bias,
pubmed-meshheading:9395148-Serotonin,
pubmed-meshheading:9395148-Spinal Puncture,
pubmed-meshheading:9395148-Students,
pubmed-meshheading:9395148-Voluntary Workers
|
pubmed:year |
1997
|
pubmed:articleTitle |
The healthy control subject in psychiatric research: impulsiveness and volunteer bias.
|
pubmed:affiliation |
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|