Linked Life Data

9394231

Source:http://linkedlifedata.com/resource/pubmed/id/9394231

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1997-12-29
pubmed:abstractText
Functional cerebral guiding and integrating systems may be revealed by analyzing the covariation of regional cerebral blood flow (rCBF). Positron emission tomography (PET) was used to measure absolute rCBF in 14 volunteers with specific phobia and 6 nonphobic controls, when exposed to videos containing phobia-relevant and neutral scenes. A fear reaction and increased covariation between absolute rCBFs was observed during phobia-relevant as compared to neutral stimulation in phobics only. In controls fear was not elicited and rCBF covariation was not influenced by stimulus condition, being similar to the pattern observed in phobics during neutral stimulation. We suggest the rCBF correlative pattern during phobic fear to reflect fear-related activation of distinct neuronal pathways that involves the amygdala, the thalamus, and the striatum. We theorize that these pathways are activated also by uncontrolled emotions in diverse conditions, like posttraumatic stress disorder, panic disorder, and schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0020-7454
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Evidence of altered cerebral blood-flow relationships in acute phobia.
pubmed:affiliation
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't