rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9091
|
pubmed:dateCreated |
1998-1-6
|
pubmed:abstractText |
Inflammatory and coagulation processes are both affected in meningococcaemia. Severe acquired protein-C deficiency in meningococcaemia is usually associated with substantial mortality: in survivors, skin grafts, amputation, and end-organ failure are not uncommon. Protein C is a natural anticoagulant and also has important anti-inflammatory activity. We assessed the effects of early replacement therapy with protein-C concentrate together with continuous veno-venous haemodiafiltration and conventional treatment in meningococcaemia.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0140-6736
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
350
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1590-3
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:9393338-Adolescent,
pubmed-meshheading:9393338-Adult,
pubmed-meshheading:9393338-Anticoagulants,
pubmed-meshheading:9393338-Child,
pubmed-meshheading:9393338-Child, Preschool,
pubmed-meshheading:9393338-Female,
pubmed-meshheading:9393338-Hemodiafiltration,
pubmed-meshheading:9393338-Heparin,
pubmed-meshheading:9393338-Humans,
pubmed-meshheading:9393338-Male,
pubmed-meshheading:9393338-Meningitis, Meningococcal,
pubmed-meshheading:9393338-Prognosis,
pubmed-meshheading:9393338-Protein C,
pubmed-meshheading:9393338-Purpura, Schoenlein-Henoch,
pubmed-meshheading:9393338-Treatment Outcome
|
pubmed:year |
1997
|
pubmed:articleTitle |
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans.
|
pubmed:affiliation |
Department of Paediatric Haematology, National Children's Hospital, Dublin, Ireland.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|