Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-12-11
pubmed:abstractText
We have previously found that conformal radiation therapy (RT) and hepatic arterial fluorodeoxyuridine was associated with durable responses and long-term survival for patients treated for nondiffuse primary hepatobiliary tumors and colorectal liver metastases. Further improvements in hepatic control may result from the addition of selective radiosensitization using bromodeoxyuridine (BrdU) infused through the hepatic artery (HA) concurrently with RT. This is a Phase I study of escalating doses of HA BrdU combined with our standard hepatic RT.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0360-3016
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1087-92
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:9392548-Adult, pubmed-meshheading:9392548-Aged, pubmed-meshheading:9392548-Bile Duct Neoplasms, pubmed-meshheading:9392548-Bile Ducts, Intrahepatic, pubmed-meshheading:9392548-Bromodeoxyuridine, pubmed-meshheading:9392548-Carcinoma, Hepatocellular, pubmed-meshheading:9392548-Cholangiocarcinoma, pubmed-meshheading:9392548-Colonic Neoplasms, pubmed-meshheading:9392548-Drug Administration Schedule, pubmed-meshheading:9392548-Female, pubmed-meshheading:9392548-Hepatic Artery, pubmed-meshheading:9392548-Humans, pubmed-meshheading:9392548-Infusions, Intra-Arterial, pubmed-meshheading:9392548-Liver Neoplasms, pubmed-meshheading:9392548-Male, pubmed-meshheading:9392548-Middle Aged, pubmed-meshheading:9392548-Radiation-Sensitizing Agents, pubmed-meshheading:9392548-Radiotherapy Dosage, pubmed-meshheading:9392548-Rectal Neoplasms
pubmed:year
1997
pubmed:articleTitle
A phase I trial of hepatic arterial bromodeoxyuridine and conformal radiation therapy for patients with primary hepatobiliary cancers or colorectal liver metastases.
pubmed:affiliation
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase I