rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
22
|
pubmed:dateCreated |
1997-12-12
|
pubmed:abstractText |
The tumor-promoting effect of ethanol on cancer of the upper respiratory-digestive tract is not well understood. Although ethanol itself is not carcinogenic, the first product of ethanol metabolism-acetaldehyde is. Acetaldehyde can be produced from ethanol by oral bacteria, and high concentrations have been observed in human saliva after ethanol consumption. The purpose of this study was to investigate whether acetaldehyde administered orally to rats induces altered differentiation and proliferation in the animals' upper gastrointestinal tracts.
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pubmed:commentsCorrections |
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0027-8874
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
89
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1692-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9390538-Acetaldehyde,
pubmed-meshheading:9390538-Animals,
pubmed-meshheading:9390538-Cell Cycle,
pubmed-meshheading:9390538-Digestive System,
pubmed-meshheading:9390538-Epithelium,
pubmed-meshheading:9390538-Ethanol,
pubmed-meshheading:9390538-Gastric Mucosa,
pubmed-meshheading:9390538-Glottis,
pubmed-meshheading:9390538-Keratins,
pubmed-meshheading:9390538-Ki-67 Antigen,
pubmed-meshheading:9390538-Male,
pubmed-meshheading:9390538-Mouth Mucosa,
pubmed-meshheading:9390538-Random Allocation,
pubmed-meshheading:9390538-Rats,
pubmed-meshheading:9390538-Rats, Wistar,
pubmed-meshheading:9390538-Tongue,
pubmed-meshheading:9390538-Tumor Markers, Biological
|
pubmed:year |
1997
|
pubmed:articleTitle |
Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa.
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pubmed:affiliation |
Research Unit of Alcohol Diseases, University Central Hospital of Helsinki, Finland.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|