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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1998-1-20
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pubmed:abstractText |
The effects of CCK-8 on the mean arterial pressure (MAP), blood components and path-morphological changes during endotoxin shock (endotoxin, 8 mg/kg b.w.iv.) in rats, as well as on the 24 h mortality rate (MR) of the lead-sensitized rats in endotoxin shock (endotoxin 1 microgram/100 g b.w.iv.) were observed. The results showed that injection of CCK in ES rats led to an increase in MAP, and a reduction of hematocrit and platelet as well as white cell count; the mortality rate decreased and the lesion in main organs lessened. It is suggested that release of endogenous CCK has important protective action during endotoxin shock.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0371-0874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
390-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9389203-Animals,
pubmed-meshheading:9389203-Endotoxins,
pubmed-meshheading:9389203-Escherichia coli,
pubmed-meshheading:9389203-Female,
pubmed-meshheading:9389203-Hematocrit,
pubmed-meshheading:9389203-Male,
pubmed-meshheading:9389203-Rats,
pubmed-meshheading:9389203-Rats, Sprague-Dawley,
pubmed-meshheading:9389203-Shock, Septic,
pubmed-meshheading:9389203-Sincalide
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pubmed:year |
1996
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pubmed:articleTitle |
[Cholecystokinin-octapeptide (CCK-8) reverses experimental endotoxin shock].
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pubmed:affiliation |
Institute of Basic Medicine, Hebei Medical University, Shijiazhuang.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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