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rdf:type |
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lifeskim:mentions |
umls-concept:C0003374,
umls-concept:C0013227,
umls-concept:C0026030,
umls-concept:C0034417,
umls-concept:C0086418,
umls-concept:C0205164,
umls-concept:C0311400,
umls-concept:C1704259,
umls-concept:C1704675,
umls-concept:C1705987,
umls-concept:C1707391
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pubmed:issue |
5
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pubmed:dateCreated |
1998-2-11
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pubmed:abstractText |
Nine antimalarial (plus two metabolites of proguanil) and twelve non-antimalarial drugs were tested for their possible interaction with CYP3A4-catalysed 3-hydroxylation of quinine by human liver microsomes in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Ketoconazole,
http://linkedlifedata.com/resource/pubmed/chemical/Nifedipine,
http://linkedlifedata.com/resource/pubmed/chemical/Omeprazole,
http://linkedlifedata.com/resource/pubmed/chemical/Primaquine,
http://linkedlifedata.com/resource/pubmed/chemical/Quinine,
http://linkedlifedata.com/resource/pubmed/chemical/Tetracycline,
http://linkedlifedata.com/resource/pubmed/chemical/Troleandomycin
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0306-5251
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
505-11
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pubmed:dateRevised |
2009-10-2
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pubmed:meshHeading |
pubmed-meshheading:9384469-Anti-Infective Agents,
pubmed-meshheading:9384469-Antimalarials,
pubmed-meshheading:9384469-Chromatography,
pubmed-meshheading:9384469-Cytochrome P-450 Enzyme System,
pubmed-meshheading:9384469-Doxycycline,
pubmed-meshheading:9384469-Drug Interactions,
pubmed-meshheading:9384469-Erythromycin,
pubmed-meshheading:9384469-Humans,
pubmed-meshheading:9384469-Hydroxylation,
pubmed-meshheading:9384469-Ketoconazole,
pubmed-meshheading:9384469-Microsomes, Liver,
pubmed-meshheading:9384469-Nifedipine,
pubmed-meshheading:9384469-Omeprazole,
pubmed-meshheading:9384469-Primaquine,
pubmed-meshheading:9384469-Quinine,
pubmed-meshheading:9384469-Tetracycline,
pubmed-meshheading:9384469-Troleandomycin
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pubmed:year |
1997
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pubmed:articleTitle |
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
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pubmed:affiliation |
Department of Clinical Pharmacology, Research Institute, International Medical Center of Japan, Tokyo.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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